4-amino-2-(trifluoromethyl)benzonitrile（CAS# 654-70-6)
| Risk Codes | R22 – Harmful if swallowed R43 – May cause sensitization by skin contact R36/37/38 – Irritating to eyes, respiratory system and skin. R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S36 – Wear suitable protective clothing. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37/39 – Wear suitable gloves and eye/face protection S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | 3439 |
| WGK Germany | 3 |
| HS Code | 29049090 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | III |
Introduction
4-Amino-2-trifluoromethylbenzonitrile is an organic compound.
Solubility: It can be dissolved in some organic solvents (such as ethanol, methylene chloride, etc.).
It can be used as an intermediate in the synthesis of other organic compounds, used in the preparation of glyphosate, chlorchlor and other pesticides, and can also be used to synthesize some bioactive molecules.
Preparation method: The preparation method of 4-amino-2-trifluoromethylbenzonitrile is generally obtained by chemical reaction. A commonly used preparation method is synthesis by cyanidation reaction, in which trifluoromethylbenzoic acid is reacted with sodium cyanide, and then undergoes a reduction reaction to obtain the target product.
Safety information: 4-amino-2-trifluoromethylbenzonitrile should pay attention to safety precautions during use, such as wearing protective gloves and glasses. Avoid inhaling its vapors or dust, and keep away from open flames and high temperatures. During storage, it should be kept in a dry and ventilated place, away from oxidants and acids. In case of accidental contact or ingestion, seek medical attention immediately. When disposing of waste, it should be disposed of in accordance with the methods prescribed by the local government.
