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4 6-dichloropyridine-3-carbonitrile(CAS# 166526-03-0)

Chemical Property:

Molecular Formula C6H2Cl2N2
Molar Mass 173
Density 1.49±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point 133-135°
Boling Point 272.9±35.0℃ (760 Torr)
Flash Point 118.8±25.9℃
Vapor Presure 0.006mmHg at 25°C
pKa -1.94±0.10(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index 1.587
MDL MFCD08276124

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Risk and Safety

Hazard Symbols T – Toxic
Risk Codes 25 – Toxic if swallowed
Safety Description 45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN2811
Hazard Class IRRITANT

4 6-dichloropyridine-3-carbonitrile(CAS# 166526-03-0) Introduction

4, is an organic compound with the chemical formula C7H3Cl2N. The following is an introduction to its nature, use, preparation and safety information:Nature:
-Appearance: 4, it is a colorless to light yellow liquid.
-Solubility: It has good solubility in general organic solvents.
-Melting point and boiling point: melting point is -10 ℃, boiling point is 230-231 ℃.
-Density: Density is 1.44g/cm³(20°C).
-Stability: It is stable, but avoid contact with strong oxidants.

Use:
- 4, is often used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize drugs such as carbamazepine.
-can also be used to synthesize a variety of pesticides and dyes.

Method:
- 4, the preparation of is usually obtained by the partial chlorination reaction of pyridine.
-The specific preparation method can be to react pyridine with benzyl chloride under acid catalysis, and then hydrolyze with concentrated aqueous hydrochloric acid to obtain 4.

Safety Information:
- 4, is an organic compound. Avoid inhalation, ingestion or skin contact.
-Wear appropriate protective equipment such as lab gloves, goggles and protective clothing when using.
-In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-Follow relevant safety procedures during storage and handling, and avoid storage with ignition sources or strong oxidants.


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