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4-(1-Pyrrolidinylsulfonylmethyl)Aniline(CAS#334981-10-1)

Chemical Property:

Molecular Formula C11H16N2O2S
Molar Mass 240.32
Density 1.31
Melting Point 170-176°C
Boling Point 434.2±47.0 °C(Predicted)
Flash Point 216.4°C
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
Vapor Presure 9.65E-08mmHg at 25°C
Appearance Solid
Color Off-White to Pale Yellow
pKa 4.35±0.10(Predicted)
Storage Condition Refrigerator
Refractive Index 1.618

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Introduction

4-Aniline is an organic compound with the chemical formula C13H18N2O2S. The following is a detailed description of its nature, use and preparation method:

 

Properties: 4-(Aniline) is a white solid powder. Its structure contains benzene ring and pyrrolidine ring, has good solubility, can be dissolved in common organic solvents.

 

Uses: 4-(-) Aniline is often used as a pharmaceutical intermediate with antibacterial and antiviral activity. It can be used to synthesize a variety of biologically active molecules, such as drugs, pesticides, etc.

 

Preparation method: The preparation of 4-(-) Aniline is usually completed by a two-step reaction. First, methanesulfonyl chloride and 4-aminoanisole are reacted to produce a sulfonyl compound. Then, the sulfonyl compound is reacted with pyrrolidine to obtain the target product.

 

Safety information: 4-(-) Aniline is an organic compound, you need to pay attention to its safe operation. Wear appropriate personal protective equipment such as goggles and gloves during operation. Avoid contact with the skin and inhalation of its powder, should be in a well-ventilated place to operate. In case of contact or ingestion, seek medical attention immediately.


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