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(3S,5S)-1-(tert-butoxycarbonyl)-5-(methoxycarbonyl)pyrrolidine-3-carboxylic acid(CAS#1378388-35-2)

Chemical Property:

Molecular Formula C12H19NO6
Molar Mass 273.28
Density 1.260±0.06 g/cm3(Predicted)
Boling Point 392.7±42.0 °C(Predicted)
pKa 4.19±0.40(Predicted)

Product Detail

Product Tags

(3S,5S)-1-(tert-butoxycarbonyl)-5-(methoxycarbonyl)pyrrolidine-3-carboxylic acid(CAS#1378388-35-2)

Structural features
The molecule contains pyrrolidine rings, which have a certain rigid structure and special spatial configuration.
T-butoxycarbonyl group (Boc) is a commonly used amino protecting group with a large steric hindrance, which can protect the amino group from interference with other reagents in organic synthesis, and can be selectively introduced and removed under specific conditions.
There is a methoxycarbonyl group at position 5, which provides a certain hydrophilicity and reactivity for the molecule, and can participate in a variety of organic reactions such as hydrolysis and alcohololysis of esters.
The carboxyl group at position 3 is acidic, and can undergo acid-base neutralization reactions, esterification reactions, etc., and can also be condensed with other amino or hydroxyl compounds.
use
As a pharmaceutical intermediate: it plays an important role in drug synthesis and can be used to synthesize a variety of biologically active drug molecules. For example, in the synthesis process of some antiviral drugs and cardiovascular drugs, it participates in the reaction as a key intermediate, and condenses and substitutes with other compounds to construct a drug structure with specific pharmacological effects.
For peptide synthesis: It can be used as one of the basic units for the construction of polypeptide chains, using its carboxyl and amino groups to condense with other amino acids, and play a role in the solid-phase synthesis or liquid-phase synthesis of polypeptides, which helps to synthesize polypeptide compounds with specific sequences and functions.


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