3-(Trifluoromethoxy)aniline (CAS# 1535-73-5)
Risk and Safety
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 – Take off immediately all contaminated clothing. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S36 – Wear suitable protective clothing. |
| UN IDs | 2810 |
| WGK Germany | 3 |
| HS Code | 29222900 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
Reference Information
| Use | for pharmaceutical and pesticide intermediates |
Introduction
M-trifluoromethoxyaniline, also known as m-Aminotrifluoromethoxybenzene. The following is an introduction to its properties, uses, manufacturing methods and safety information:
Quality:
- Appearance: colorless or light yellow solid;
- Solubility: slightly soluble in water, soluble in organic solvents such as alcohols and ethers.
Use:
- In chemical reactions, it is often used as a starting point for the introduction of trifluoromethoxy groups into amino and aromatic compounds.
Method:
- m-trifluoromethoxyaniline can be synthesized by introducing trifluoromethoxy groups at the interposition of aniline molecules;
- Specifically, trifluoromethyl aromatization reagents can be used to react with aniline.
Safety Information:
- M-trifluoromethoxyaniline is irritating under certain conditions and may be harmful to the eyes, skin and respiratory tract;
- Care should be taken to prevent inhalation, contact and ingestion, and protective eyewear and gloves should be worn;
- Proper ventilation systems should be equipped during operation to ensure that operations are carried out in well-ventilated areas;
- In case of accidental contact with the substance, rinse immediately with water and seek medical help
