3-methyl-2-oxobutyric acid （CAS# 759-05-7)

Introduction

3-Methyl-2-oxobutyric acid, also known as tert-butoxypropionic acid, TBAOH, is an organic compound.

Quality:

3-Methyl-2-oxobutyric acid is a colorless to pale yellow liquid with a peculiar odor. It can be soluble in water and many organic solvents, but insoluble in non-polar solvents such as petroleum ethers.

Use:

3-Methyl-2-oxobutyric acid is often used as an alkali catalyst in organic synthesis, especially in substitution reactions. It can catalyze reactions such as esterification, etherification, amidation, olefin addition, etc. It can also be used as a liquid-phase catalyst to catalyze reactions such as oxidation, hydrogenation, and alkydation.

Method:

3-Methyl-2-oxobutyric acid can be obtained by reacting propanol with sodium tert-butoxide (or tert-butanol and sodium hydroxide). The specific step is to react propanol with tert-butyl sodium oxide at an appropriate temperature, and then the product is obtained by deactivation.

Safety Information:

3-Methyl-2-oxobutyric acid is irritating and corrosive and should be avoided from contact with the skin, eyes, and respiratory tract. Protective gloves, goggles, and masks should be worn during use. In case of accidental contact, rinse with plenty of water and seek medical attention immediately. It should be stored in a cool, ventilated place, away from fire and oxidants.