3-Fluoro-5-bromobenzyl bromide（CAS# 216755-57-6)
| Risk Codes | 25 – Toxic if swallowed |
| Safety Description | 45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Class | 8 |
Introduction
3-Fluoro-5-bromobenzyl bromide is an organic compound with the chemical formula C7H5Br2F. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting Point: 48-51 ℃
-Boiling Point: 218-220 ℃
-Stability: stable under dry conditions, but hydrolyzed in the presence of moisture
-Solubility: Soluble in organic solvents, such as ethanol, ether
Use:
3-Fluoro-5-bromobenzyl bromide is commonly used as an intermediate in organic synthesis and can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes. It can also be used as a ligand to form complexes with metals and play an important role in catalytic reactions.
Method:
3-Fluoro-5-bromobenzyl bromide can be synthesized by the following steps:
1. 3-fluorobenzyl is reacted with bromine in chloroform to obtain 3-fluoro-3-bromobenzyl.
2. The product obtained in the previous reaction is reacted with bromine in ethanol to obtain the final product 3-Fluoro-5-bromobenzyl bromide.
Safety Information:
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This is a highly alkyl compound with strong deliquescence and needs to be properly preserved to avoid moisture. Pay attention to the following safety matters in operation:
- 3-Fluoro-5-bromobenzyl bromide is irritating and should avoid inhalation of gas or steam, and avoid contact with skin and eyes.
-During use or storage, a well-ventilated environment should be maintained.
-When exposed to this compound, immediately rinse the affected area with plenty of water and seek help from a doctor.
-Wear appropriate personal protective equipment such as chemical protective gloves, goggles and protective clothing during operation.
