3-Fluoro-4-nitrobenzoic acid（CAS# 403-21-4)
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R37/38 – Irritating to respiratory system and skin. R36 – Irritating to the eyes R22 – Harmful if swallowed |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S37 – Wear suitable gloves. |
| HS Code | 29163990 |
| Hazard Class | IRRITANT |
Introduction
3-Fluoro-4-nitrobenzoic acid is an organic compound with the chemical formula C7H4FNO4. The following is a description of some properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: White or slightly yellow crystal, or light yellow to yellowish brown powder.
-Melting point: 174-178 degrees Celsius.
-Boiling point: 329 degrees Celsius.
-Solubility: Soluble in alcohol and organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
- 3-Fluoro-4-nitrobenzoic acid is an important intermediate, widely used in the field of organic synthesis.
-It is commonly used in drug synthesis and dye synthesis.
-This compound can also be used as a raw material for dyes, pesticides and explosives.
Preparation Method:
The preparation method of 3-Fluoro-4-nitrobenzoic acid generally includes the following steps:
1. 4-Nitrobenzoic acid is reacted with hydrogen fluoride to obtain 3-nitro-4-fluorobenzoic acid.
2. The product obtained in the previous step is reacted with sulfuric acid to obtain 3-Fluoro-4-nitrobenzoic acid.
Safety Information:
- 3-Fluoro-4-nitrobenzoic acid may be irritating to the eyes, skin, and respiratory tract. Pay attention to the use of personal protective equipment during contact.
-It should be stored in a dark, dry and sealed container, away from fire and oxidizing agents.
-In use and handling, should follow the relevant safety procedures, and maintain good ventilation.
