3-Cyanopyridine(CAS#100-54-9)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R22 – Harmful if swallowed R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | QT3030000 |
| TSCA | Yes |
| HS Code | 29333999 |
3-Cyanopyridine(CAS#100-54-9)
Introduction3-Cyanopyridine is an organic compound with the chemical formula C6H4N2, where a cyano group (-CN) replaces one hydrogen atom on the pyridine ring.3-Cyanopyridine has the following properties:1. It appears as colorless to light yellow crystalline or powdered solid.2. It has a strong odor at room temperature.3. It has low melting and boiling points.4. It is soluble in organic solvents, such as ethanol and ether.5. It is stable in air but can easily decompose when heated, producing toxic gases.The main uses of 3-cyanopyridine include:1. As an intermediate in organic synthesis, it can be used to synthesize other compounds, such as dyes.2. As a ligand for organometallic catalysts.There are mainly two methods for preparing 3-cyanopyridine:1. The Babel reaction: reacting pyridine with hydrogen cyanide in the presence of a suitable catalyst to produce 3-cyanopyridine.2. The Kasztrowicz reaction: reacting 3-bromopyridine with sodium cyanide to generate 3-cyanopyridine.1. 3-Cyanopyridine is irritating and should be avoided for direct contact with skin and eyes.2. Protective gloves, safety glasses, and protective clothing should be worn during operation.3. Operate in a well-ventilated area to avoid inhaling the vapors of this compound.4. Avoid vigorous reactions with oxidizing agents, strong acids, and strong bases.5. Store in a sealed container in a cool, dry place, away from heat and ignition sources.When using and handling 3-cyanopyridine, strict adherence to relevant safety operating procedures should be followed to ensure the safety of the working environment.
