3-Chloro-4-fluorobenzyl bromide（CAS# 192702-01-5)

3-Chloro-4-fluorobenzyl bromide is an organic compound with the chemical formula C7H5BrClF. The following is a description of its nature, use, preparation and safety information:Nature:
3-Chloro-4-fluorobenzyl bromide is a solid with a characteristic odor similar to bromobenzene. It has a melting point of about 38-39 ° C. And a boiling point of about 210-212 ° C. At room temperature, it is almost insoluble in water, but soluble in most organic solvents.

Use:
3-Chloro-4-fluorobenzyl bromide has a wide range of applications in organic synthesis. It is an important intermediate for the preparation of other organic compounds, such as drugs, dyes and pesticides. It is also used in the preparation of flame retardants, photosensitive materials and resin modifiers.

Method:
3-Chloro-4-fluorobenzyl bromide is generally obtained by reacting bromobenzene with tert-butyl magnesium bromide. First, tert-butylmagnesium bromide is reacted with bromobenzene at a low temperature to obtain tert-butylphenylcarbinol. Then, by chlorination and fluorination, the carbinol groups can be converted to chlorine and fluorine, and 3-Chloro-4-fluorobenzyl bromide is formed. Finally, the target product can be obtained by purification by distillation.

Safety Information:
Use 3-Chloro-4-fluorobenzyl bromide with attention to toxicity and irritation. It may cause irritation to the respiratory system, skin and eyes. Avoid contact with skin, eyes and respiratory tract during operation. Wear appropriate protective equipment, such as gloves, goggles and face shields. In addition, it should be stored in a well-ventilated place and avoid contact with substances such as strong oxidants. If swallowed or inhaled, seek medical attention immediately. Please read the product safety instructions carefully before use.