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3-Chloro-4-fluoroaniline(CAS#367-21-5)

Chemical Property:

Molecular Formula C6H5ClFN
Molar Mass 145.56
Density 1,226 g/cm3
Melting Point 42-44 °C (lit.)
Boling Point 227-228 °C (lit.)
Flash Point >230°F
Water Solubility 10 g/L (20 ºC)
Solubility 10g/l
Vapor Presure 0.01 hPa (20 °C)
Appearance Crystalline Solid
Color Beige to brown
BRN 1562786
pKa 3.60±0.10(Predicted)
PH 7 (10g/l, H2O, 20℃)
Storage Condition Store below +30°C.
Stability Stable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates. May be air-sensitive.
Refractive Index 1,54-1,542
Physical and Chemical Properties Melting point 42-47°C
boiling point 230°C
flash point 149°C
water-soluble 10g/L (20°C)
Use Is an important intermediate in the synthesis of norfloxacin

Product Detail

Product Tags

Risk Codes R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R33 – Danger of cumulative effects
R36/37/38 – Irritating to eyes, respiratory system and skin.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs UN 2811 6.1/PG 2
WGK Germany 2
FLUKA BRAND F CODES 9-23
TSCA T
HS Code 29214210
Hazard Note Irritant/Toxic
Hazard Class 6.1
Packing Group III
Toxicity LD50 orally in Rabbit: 506 mg/kg

 

Introduction

3-Chloro-4-fluoroaniline is an organic compound. It is a colorless to yellowish crystal with a special smell.3-Chloro-4-fluoroaniline has a wide range of uses. In the chemical industry, it can be used as an intermediate for dyes and pigments in the production of dyes, pigments and coatings.There are several ways to prepare 3-chloro-4-fluoroaniline. A common method is to react 4-fluorobenzene chloride with ammonia to obtain 3-chloro-4-fluoroaniline. The specific reaction conditions and steps can be adjusted according to the actual needs.Safety information, 3-chloro-4-fluoroaniline is generally relatively safe under normal use conditions. As a chemical, it can still pose some level of risk to health and the environment. Appropriate safety measures such as wearing protective gloves, glasses, and masks should be taken when handling and storing. Avoid contact with oxidizing agents and strong acids to avoid initiating dangerous chemical reactions. In case of accidental conditions such as inhalation, skin contact or accidental ingestion, seek medical attention immediately. When using or handling 3-chloro-4-fluoroaniline, be sure to refer to the relevant safety operating procedures and follow the safety measures of the laboratory.


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