3-bromo-5-chloropyridine-2-carbonitrile(CAS#760207-83-8)

Introduction

It is an organic compound with the chemical formula C6H2BrClN2. The following is a description of its nature, use, preparation and safety information:

Nature:

-Appearance: It is a solid with white to light yellow crystals.

-Solubility: It is soluble in some polar solvents (such as alcohols, ethers and dimethylformamide).

-Melting point and boiling point: Its melting point is about 85-87°C.

-Chemical properties: It can be used as a ligand to participate in reactions such as chloride and bromide, and can be used in organic synthesis reactions.

Use:

-It can be used as an intermediate in organic synthesis for the synthesis of other drugs, pesticides and chemicals.

-It can also be used to synthesize natural products and other organic compounds containing pyridine structure.

Preparation Method:

It can be synthesized by the following steps:

1. In dichloromethane or chloroform, 2-cyano -3-bromine pyridine and silver chloride reaction, the formation of silver salt.

2. The above silver salt is reacted with trifluoroacetic acid in dichloromethane to generate phosphonium.

Safety Information:

-should be stored in a cool, dry place, away from direct sunlight and moisture.

-During operation, wear appropriate protective equipment, such as gloves, glasses and laboratory coats, to avoid contact with skin and eyes.

-Observe relevant safe operation guidelines during storage and handling, and follow local regulations and codes.