3-Amino-4-fluorobenzotrifluoride（CAS# 535-52-4)
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. R23 – Toxic by inhalation R21/22 – Harmful in contact with skin and if swallowed. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 – Wear suitable protective clothing and gloves. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN2810/6.1/II |
| WGK Germany | 3 |
| HS Code | 29214200 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
Introduction
2-Fluoro-5-trifluoromethylaniline is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
- Appearance: Colorless crystals or solid powders.
- Solubility: soluble in organic solvents, such as ethanol, dimethylformamide, etc., insoluble in water.
Use:
2-Fluoro-5-trifluoromethylaniline is an important chemical intermediate and is often used in organic synthesis reactions. It can also be used in the synthesis of dyes and coatings and in the preparation of electronic materials.
Method:
The preparation of 2-fluoro-5-trifluoromethylaniline can be carried out by the following steps:
Fluoroaniline is reacted with trifluorocarboxylic acid in an appropriate solvent to produce trifluoroformate of 2-fluoro-5-trifluoromethylaniline.
Trifluoroformate is reacted with a base to produce 2-fluoro-5-trifluoromethylaniline under the action of the base.
Safety Information:
The following safety precautions should be taken when handling 2-fluoro-5-trifluoromethylaniline:
- It is an organic substance and has a certain toxicity. Contact or inhalation of the substance may pose a health hazard and direct contact with the skin and eyes should be avoided.
- Wear appropriate personal protective equipment such as chemical goggles, gloves and protective clothing when operating.
- Operate under closed ventilation conditions to avoid inhalation of harmful gases.
- Keep away from fire and high temperatures when storing, and avoid contact with oxidants and strong acids.
- When using or handling the substance, the relevant safety operating procedures should be strictly followed. In case of any accidents, take appropriate first aid measures and seek medical assistance immediately.
