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3 5-Bis(trifluoromethyl)aniline(CAS# 328-74-5)

Chemical Property:

Molecular Formula C8H5F6N
Molar Mass 229.12
Density 1.467g/mLat 25°C(lit.)
Melting Point 168.2-169.2 °C
Boling Point 85°C15mm Hg(lit.)
Flash Point 182°F
Water Solubility Not miscible in water.
Vapor Presure 0.405mmHg at 25°C
Appearance Liquid
Specific Gravity 1.473
Color Clear light yellow to yellow-brown
BRN 654318
pKa 2.15±0.10(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index n20/D 1.434(lit.)
Physical and Chemical Properties Colorless transparent liquid, irritating. The boiling point is 85 °c/15mmHg, the flash point is 83 °c, the relative density is 1.473, and the refractive index is 1.434.
Use Used as pharmaceutical, pesticide intermediates

Product Detail

Product Tags

Risk Codes R33 – Danger of cumulative effects
R36/37/38 – Irritating to eyes, respiratory system and skin.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S36 – Wear suitable protective clothing.
UN IDs 2810
WGK Germany 3
RTECS ZE9800000
TSCA Yes
HS Code 29214910
Hazard Note Irritant
Hazard Class 6.1
Packing Group III

 

Introduction

3,5-Bis(trifluoromethyl)aniline, also known as 3,5-bis(trifluoromethyl)aniline, is an organic compound.

 

Quality:

3,5-Bis(trifluoromethyl)aniline is a colorless to pale yellow crystal that is solid at room temperature. It is almost insoluble in water at room temperature but soluble in organic solvents such as ethanol, ether, and methylene chloride. It has high thermal and chemical stability.

 

Use:

3,5-Bis(trifluoromethyl)aniline is widely used as a reagent in organic synthesis. It can be used as a fluorinating reagent for aromatic compounds and heterocyclic compounds for the introduction of trifluoromethyl groups.

 

Method:

The preparation of 3,5-bis(trifluoromethyl)aniline is usually made by organic synthesis method. A common synthesis method is to react fluoromethyl reagent with aniline to synthesize the target compound by introducing a trifluoromethyl group.

 

Safety Information:

When using or handling 3,5-bis(trifluoromethyl)aniline, the following safety concerns should be noted:

It is an organic compound and should be avoided from contact with the skin, eyes, and internal digestive tract. Wear appropriate personal protective equipment such as gloves, protective eyewear, and a lab coat when operating.

Good laboratory practice and safety guidelines should be followed when operating.

During storage and handling, avoid contact with oxidants, acids and alkalis, and flammable substances to avoid the generation of hazardous substances.

Waste disposal should comply with local regulations, and dumping in the natural environment is strictly prohibited.

 


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