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3-[(3-amino-4-methylamino-benzoyl)pyridin-2-yl-amino]-(CAS# 212322-56-0)

Chemical Property:

Molecular Formula C18H22N4O3
Molar Mass 342.4
Density 1.261±0.06 g/cm3(Predicted)
Melting Point 104.0 to 108.0 °C
Boling Point 576.2±50.0 °C(Predicted)
Flash Point 302.248°C
Solubility DMSO (Slightly), Methanol (Slightly)
Vapor Presure 0mmHg at 25°C
Appearance Solid
Color Off-White to Pale Beige
pKa 5.37±0.11(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index 1.64

Product Detail

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Introduction

N-[4-methylamino-3-aminobenzoyl]N-2-pyridyl-b-alanine ethyl ester, often abbreviated as AAPB, is a chemical compound. The following is an introduction to the nature, use, manufacturing method and safety information of AAPB:

 

Quality:

- Appearance: Generally white to light yellow crystalline solid.

- Solubility: Soluble in organic solvents such as dimethyl sulfoxide and methylene chloride, insoluble in water.

- Chemistry: AAPB is hydrolyzed under acidic conditions and can react with amines as well as aromatic aldehydes and ketones.

 

Use:

AAPB is often used as an intermediate in organic synthesis and can be used to prepare compounds containing pyridine or benzamide structures.

 

Method:

The preparation method of AAPB is relatively complex and generally involves a multi-step reaction. The main synthetic pathway typically involves the reaction of raw materials such as pyridone and ethyl para-aminobenzoate, which is carried out through a series of steps.

 

Safety Information: As an organic compound, it may have toxic effects on humans and appropriate laboratory safety measures should be taken, such as wearing protective equipment and operating under well-ventilated laboratory conditions. It is also necessary to avoid contact with oxidants and strong acids.


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