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(2S 3aS 7aS)-Octahydro-1H-indole -2-carboxylic Acid(CAS# 80875-98-5)

Chemical Property:

Molecular Formula C9H15NO2
Molar Mass 169.22
Density 1.135±0.06 g/cm3(Predicted)
Melting Point 275-277°C
Boling Point 318.6±25.0 °C(Predicted)
Flash Point 146.5°C
Water Solubility Soluble in methanol and water.
Solubility Methanol (Sparingly), Water (Slightly)
Vapor Presure 7.54E-05mmHg at 25°C
Appearance White solid
Color White to Off-White
pKa 2.47±0.20(Predicted)
PH -50 (c=1 in methanol)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index 1.507
MDL MFCD07782125
Use Perindopril intermediate.

Product Detail

Product Tags

Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37 – Wear suitable gloves.
HS Code 29339900

 

Introduction

(2S,3As,7As)-Octahydro-1H-indole-2-carboxylic acid, also known as octahydro-1H-indole-2-carboxylic acid, is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:

 

Quality:

- (2S,3As,7As)-Octahydro-1H-indole-2-carboxylic acid is a white crystalline solid.

- It has an indole backbone in which the hydrogen atom is replaced by an oxygen atom to form carboxylic acids.

- It is a chiral compound with two chiral centers with four possible stereoisomers.

 

Use:

- It is widely used in the pharmaceutical field as a blocking protective group to control the stereoselectivity of certain chemical reactions.

- It is also used as an intermediate in the synthesis of biologically active compounds.

 

Method:

- (2S,3As,7As)-Octahydro-1H-indole-2-carboxylic acid can be formed by the reaction of indole synthesis with aldehyde and ketone compounds.

 

Safety Information:

- When using or handling (2S, 3As, 7As)-Octahydro-1H-indole-2-carboxylic acid, the safe operating procedures of chemical laboratories should be observed.

- It can have an irritating effect on the eyes, skin, and mucous membranes, and care must be taken to avoid contact.

- Use appropriate personal protective equipment such as lab gloves, lab goggles, and lab coats.

- When storing and handling the compound, follow the relevant storage and handling guidelines and avoid contact with incompatible substances.


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