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2,5-Difluoroaniline(CAS#367-30-6)

Chemical Property:

Molecular Formula C6H5F2N
Molar Mass 129.11
Density 1.288 g/mL at 25 °C (lit.)
Melting Point 11-13 °C (lit.)
Boling Point 176-178 °C (lit.)
Flash Point 156°F
Water Solubility Not miscible in water.
Vapor Presure 0.009mmHg at 25°C
Specific Gravity 1.29
BRN 2802549
pKa 2.19±0.10(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index n20/D 1.513(lit.)
Physical and Chemical Properties Boiling point 176 ℃-178 ℃, melting point 13 ℃-14 ℃, flash point 68 ℃, refractive index 1.5130, specific gravity 1.288.
Use Used as a pharmaceutical Intermediate

Product Detail

Product Tags

Risk Codes R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S28 – After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
UN IDs 2941
WGK Germany 3
FLUKA BRAND F CODES 8-10-23
HS Code 29214210
Hazard Note Irritant
Hazard Class 6.1
Packing Group III

 

Introduction

2,5-Difluoroaniline.Quality:2,5-Difluoroaniline is a colorless to yellowish crystalline solid. It is stable at room temperature and slightly soluble in water, but easily soluble in organic solvents. It is a hydrophobic amine that has the characteristics of an aromatic amine and is prone to aromatic electron substitution reactions.Use:2,5-Difluoroaniline is often used as an important intermediate and starting substance in organic synthesis. It can also be used as a light-emitting layer material in organic light-emitting diodes (OLEDs).Method:In general, the preparation of 2,5-difluoroaniline can be achieved by introducing a fluorine atom at the position of aminobenzene. One synthesis method is to use chlorofluorodifluoromethane as a fluorine source, react with aminobenzene, and carry out nucleophilic aromatic substitution reaction under alkaline conditions to generate 2,5-difluoroaniline.Safety Information:2,5-Difluoroaniline is a toxic compound that is irritating and corrosive. When using or storing, care should be taken to avoid contact with the skin, eyes and respiratory tract. Appropriate personal protective equipment such as gloves, goggles, and protective clothing should be worn during operation. Avoid contact with strong oxidizing agents and acids to prevent dangerous reactions. When disposing of waste, relevant laws and regulations should be complied with and appropriate disposal measures should be taken.


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