2,4-Difluorobenzonitrile(CAS#3939-9-1)
2,4-Difluorobenzonitrile(CAS#3939-9-1)
use
Medicine: It can be used to synthesize drugs for the treatment of neurological diseases, such as drugs for the treatment of Alzheimer’s disease. Some compounds synthesized from 2,4-difluorobenzonitrile have potential applications for the treatment of neurodegenerative diseases.
Pesticide field: used to synthesize new green pesticides, with strong selectivity, low use, low toxicity to humans, low residue and other advantages, in line with the development direction of modern pesticides, help to reduce the pollution of pesticides to the environment and the impact on non-target organisms.
Materials science: As a molecular building block, it is used to prepare organic light-emitting diode (OLED) materials, photoredox catalysts, etc., and plays an important role in the field of materials science and organic synthesis. For example, complexes formed with iridium have high quantum yields of blue light emission and have potential applications in OLED display technology.
Synthesis method
Haloaromatic hydrocarbon cyanidation method: 2,4-difluorochlorobenzene is used as raw material, and cyanide reaction occurs with cyanide reagents such as zinc cyanide under appropriate reaction conditions to generate 2,4-difluorobenzonitrile.
Other methods: It can also be synthesized by the functional group conversion reaction of other fluorobenzene derivatives, such as the dehydration reaction of fluorobenzaldehyde oxime, the amidation-dehydration reaction of fluorobenzoic acid, etc.