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2,4-Difluoroaniline(CAS#367-25-9)

Chemical Property:

Molecular Formula C6H5F2N
Molar Mass 129.11
Density 1.268 g/mL at 25 °C (lit.)
Melting Point -7.5 °C (lit.)
Boling Point 170 °C/753 mmHg (lit.)
Flash Point 145°F
Water Solubility 1-5 g/100 mL at 20.55 ºC
Solubility Not miscible or difficult to mix.
Vapor Presure 3.8mmHg at 25°C
Appearance Liquid
Specific Gravity 1.284 (20/4℃)
Color Clear brown
Merck 14,3147
BRN 2802556
pKa 3.26±0.10(Predicted)
Storage Condition Keep in dark place,Inert atmosphere,2-8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
Refractive Index n20/D 1.506(lit.)
Physical and Chemical Properties Characteristic light yellow oily substance.
melting point -75 ℃
boiling point 169.5 ℃(97.2kPa)
refractive index 1.5063
flash point 62 ℃
Use Used as intermediates in the synthesis of pharmaceuticals, pesticides and dyes

Product Detail

Product Tags

Risk Codes R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S28 – After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
UN IDs UN 2941 6.1/PG 3
WGK Germany 1
RTECS BX3680000
FLUKA BRAND F CODES 8-9-23
TSCA T
HS Code 29214210
Hazard Note Toxic
Hazard Class 6.1
Packing Group III

 

Introduction

2,4-Difluoroaniline is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:Quality:2,4-Difluoroaniline is a colorless to pale yellow crystal with a peculiar odor. It is soluble in water and can also be soluble in most organic solvents.Uses: In chemical synthesis, it can be used as a derivative of amides, amide chain extenders and aromatic amines for the introduction of aniline groups in the synthesis process.Method:The preparation method of 2,4-difluoroaniline can be achieved by the reduction of p-fluorobenzene. A common method is to react fluorobenzene with sodium nitrite under acidic conditions to produce nitrosobenzene, which is then reduced to 2,4-difluoroaniline using a reducing agent such as iron powder.Safety Information:2,4-Difluoroaniline has certain toxicity under certain conditions. It is irritating and can cause damage to the eyes, skin, respiratory tract and digestive system. Appropriate personal protective equipment such as gloves and protective eyewear should be worn when using and handling this compound. It needs to be operated in a well-ventilated environment to avoid inhaling its vapors or coming into contact with its solutions.


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