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2-THIOADENOSINE(CAS#43157-50-2)

Chemical Property:

Molecular Formula C10H13N5O4S
Molar Mass 299.31
Density 2.18±0.1 g/cm3(Predicted)
Melting Point >178°C (dec.)
Boling Point 544.5±60.0 °C(Predicted)
Solubility Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Appearance Solid
Color Pale Yellow to Yellow
pKa 8.37±0.40(Predicted)
Storage Condition 2-8°C(protect from light)

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Introduction

Adenosine-2-thion is an organic compound that belongs to the nucleoside group. Adenosine-2-thione is a white or off-white crystalline powder at room temperature and is soluble in water and some organic solvents.Adenosyl-2-thione has an important use in biochemical research. It is a novel tool compound capable of influencing RNA through nucleotide modifications. Studies have found that adenosyl-2-thione can interfere with the normal function of RNA, thereby exerting a regulatory role. It is widely used to study biological processes such as RNA interactions and translational regulation.The preparation method of adenosine-2-thione can be obtained by chemical synthesis. Typically, it can be synthesized by reacting adenosine with thiochloride sulfoxide (SOCl2). The specific synthesis steps and conditions can be adjusted according to the needs of the experiment.Safety information of adenosyl-2-thione: no clear reports have been made. As an organic compound, it can have some toxicity. When using and handling adenosine-2-thione, follow safe laboratory practices such as wearing appropriate personal protective equipment (such as gloves and goggles), good ventilation, and avoiding contact with eyes, skin, or mouth. When handling and storing adenosine-2-thione, the appropriate guidelines for safe handling of chemicals should be followed.


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