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2-Methyl-5-nitropyridine(CAS# 21203-68-9)

Chemical Property:

Molecular Formula C6H6N2O2
Molar Mass 138.12
Density 1.246±0.06 g/cm3(Predicted)
Melting Point 112 C
Boling Point 237.1±20.0 °C(Predicted)
Flash Point 97.195°C
Water Solubility Slightly soluble in water.
Vapor Presure 0.07mmHg at 25°C
Appearance Solid
Color Light yellow to Brown
pKa 1.92±0.10(Predicted)
Storage Condition Inert atmosphere,Room Temperature
Refractive Index 1.558
MDL MFCD04114179

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.

 

Introduction

2-methyll-5-nitropyridine is an organic compound with the chemical formula C6H6N2O2, which has the following properties:

 

1. Appearance: colorless to light yellow crystal;

2. Smell: no special smell;

3. Melting Point: 101-104 degrees Celsius;

4. Solubility: almost insoluble in water, soluble in organic solvents such as ethanol and dichloromethane.

 

2-Methyl-5-nitropyridine is mainly used as a raw material and intermediate in organic synthesis and pharmaceutical industry. It can be used for the synthesis of pyridine and thiophene compounds, and can also be used for the preparation of pesticides, dyes and some compounds in the field of medicine.

 

The preparation of 2-methyll-5-nitropyridine can be carried out by the following steps:

1.2-pyridine acetic acid and sodium nitrite are reacted under acidic conditions to generate 2-nitropyridine.

2. The reaction of 2-Nitro pyridine with methylating reagent (such as methyl iodide) to generate 2-Methyl-5-nitropyridine.

 

When using and storing 2-methyll-5-nitropyridine, you need to pay attention to the following safety information:

-It is a combustible, avoid contact with fire;

-Pay attention to protective measures during operation, such as wearing protective glasses and gloves;

-avoid inhalation of its gas or dust, avoid skin contact;

-Store in a closed container, away from fire and oxidizing agents;

-Avoid mixing with strong oxidants or strong acids.


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