2-Fluoronicotinic acid（CAS# 393-55-5)
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R10 – Flammable |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S16 – Keep away from sources of ignition. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
Introduction
2-Fluoronicotinic acid is an organic compound with the chemical formula C6H4FNO2. It is a derivative of nicotinic acid (3-oxopyridine-4-carboxylic acid) in its chemical structure, in which one hydrogen atom is replaced by a fluorine atom.
2-Fluoronicotinic acid is a white crystalline solid that is stable at ambient temperature. It has good solubility and can be dissolved in water. It is a weak acid that forms salts with metals.
2-Fluoronicotinic acid is widely used in some fields. It can be used as an important intermediate in organic synthesis for the preparation of other compounds or drugs. In addition, it can also be used in metal coordination chemistry and catalytic reactions.
There are various methods for preparing 2-Fluoronicotinic acid. A common method is by fluorination of nicotinic acid. A common method is the reaction of a fluorinating reagent, such as hydrogen fluoride or trifluoroacetic acid, with nicotinic acid under acidic conditions to give 2-Fluoronicotinic acid.
Safety considerations are required when handling 2-Fluoronicotinic acid. It is a corrosive compound and should be worn with appropriate protective gloves and glasses. Avoid inhaling its dust or vapor during use, and maintain a well-ventilated laboratory environment. When storing, it needs to be kept in a dry, sealed container, away from combustibles and oxidants.
In general, 2-Fluoronicotinic acid is an organic compound with good solubility and stability. It has a wide range of applications in organic synthesis, metal coordination and catalytic reactions, but safety precautions need to be taken during handling and storage.
