2-Fluoroanisole（CAS# 321-28-8)
| Risk Codes | R10 – Flammable R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S16 – Keep away from sources of ignition. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S27 – Take off immediately all contaminated clothing. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| HS Code | 29093090 |
| Hazard Note | Flammable |
| Hazard Class | 3 |
| Packing Group | III |
Introduction
O-fluoroanisole (2-fluoroanisole) is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of o-fluoroanisole:
Quality:
- O-fluoroanisole is a flammable liquid that is denser than water.
- Low vapor pressure and low solubility at room temperature.
- It is a polar solvent that is soluble in alcohols, ethers, aromatics, and other organic solvents.
Use:
- O-fluoroanisole is often used as a catalyst, solvent and intermediate in organic synthesis.
- In organic synthesis, it is commonly used in the fluorination reaction of benzene ring and the synthesis of esters.
- It can also be used as a reagent or solvent for research compounds.
Method:
- The most commonly used method for the preparation of o-fluoroanisole is the etherolysis of fluoroborate.
- The specific preparation method is to react phenol with fluoroborate to form ether, followed by deprotection reaction to obtain o-fluoroanisole.
Safety Information:
- O-fluoroanisole is a flammable liquid and should be stored in a cool, well-ventilated place, away from open flames and high-temperature items.
- Wear appropriate personal protective equipment, including respirators, gloves, and protective eyewear, during handling.
- Avoid contact with skin and eyes, and avoid inhaling their vapors.
- When handling this compound, safe operating procedures should be strictly followed and waste should be disposed of properly.
