2-Fluoro-5-nitropyridine（CAS# 456-24-6)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R22 – Harmful if swallowed |
| Safety Description | 36 – Wear suitable protective clothing. |
| UN IDs | UN 1549 |
Introduction
2-Fluoro-5-nitropyridine (2-Fluoro-5-nitropyridine) is an organic compound with the chemical formula C5H3FN2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Fluoro-5-nitropyridine is a white to pale yellow solid.
-Solubility: It can be dissolved in many organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point is about 78-81 degrees Celsius.
Use:
- 2-Fluoro-5-nitropyridine is an effective organic synthesis intermediate, which has important uses in the manufacture of drugs and pesticides.
-It can be used to synthesize a variety of biologically active compounds, such as pharmaceuticals, dyes and coatings.
Preparation Method:
- 2-Fluoro-5-nitropyridine is generally prepared by the fluorination and nitration of pyridine.
-The specific preparation method may be reacting pyridine with hydrogen fluoride or ammonium fluoride to obtain 2-fluoropyridine. The 2-fluoropyridine is then reacted with nitric acid to give 2-Fluoro-5-nitropyridine.
Safety Information:
- 2-Fluoro-5-nitropyridine is an organic compound with a certain degree of danger. In the process of operation, it is necessary to abide by the relevant safety operation regulations.
-It may be irritating to the skin and eyes, so protective measures should be taken when exposed, such as wearing protective gloves and goggles.
-If accidentally ingested or inhaled, seek medical attention and give appropriate first aid measures.
-During storage, 2-Fluoro-5-nitropyridine should be stored in a dry, cool place, away from fire and oxidizing agents.
