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2-Fluoro-5-bromopyridine (CAS# 766-11-0)

Chemical Property:

Molecular Formula C5H3BrFN
Molar Mass 175.99
Density 1.71g/mLat 25°C(lit.)
Boling Point 162-164°C750mm Hg(lit.)
Flash Point 165°F
Solubility DMSO (Slightly), Methanol (Slightly)
Vapor Presure 1.37mmHg at 25°C
Appearance Liquid
Specific Gravity 1.710
Color Clear colorless yellow
BRN 1363171
pKa -2.79±0.10(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index n20/D 1.5325(lit.)
Physical and Chemical Properties Colorless transparent liquid

Product Detail

Product Tags

Risk Codes R36/37/38 – Irritating to eyes, respiratory system and skin.
R22 – Harmful if swallowed
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 – Wear suitable protective clothing and gloves.
S37/39 – Wear suitable gloves and eye/face protection
UN IDs UN2810
WGK Germany 3
HS Code 29339900
Hazard Note Irritant
Hazard Class 6.1
Packing Group III

 

Introduction

5-Bromo-2-fluoropyridine is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:

 

Quality:

Appearance: 5-bromo-2-fluoropyridine is a colorless to light yellow solid.

Solubility: It is soluble in organic solvents such as ethanol, dimethylformamide (DMF) and dichloromethane.

 

Use:

Chemical synthesis: 5-bromo-2-fluoropyridine can be used as an intermediate in organic synthesis and plays an important role in the preparation of other organic compounds.

 

Method:

In general, the method for preparing 5-bromo-2-fluoropyridine consists of the following steps:

Pyridine is reacted with hydrogen fluoride to give 2-fluoropyridine.

2-Fluoropyridine is reacted with bromine under alkaline conditions to obtain 5-bromo-2-fluoropyridine.

 

Safety Information:

Safety: 5-Bromo-2-fluoropyridine may be harmful to health and the environment, and relevant safety operating procedures should be followed. Direct contact with skin and eyes should be avoided during use, and good ventilation should be ensured.

Storage: 5-Bromo-2-fluoropyridine should be stored in an airtight container, away from fire and flammable substances.

Waste disposal: According to local regulations, the waste 5-bromo-2-fluoropyridine should be properly disposed of in accordance with the relevant regulations.

 


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