2-Fluoro-5-bromo-3-methylpyridine（CAS# 29312-98-9)
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. R41 – Risk of serious damage to eyes R37/38 – Irritating to respiratory system and skin. R22 – Harmful if swallowed |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S39 – Wear eye / face protection. S37 – Wear suitable gloves. |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
Introduction
It is an organic compound with the chemical formula C7H6BrFN.
Nature:
-Appearance: Colorless to light yellow liquid
-Melting point:-3 ℃
-Boiling point: 204-205 ℃
-Density: 1.518g/cm³
-Solubility: Slightly soluble in water, soluble in most organic solvents
Use:
It is mainly used in organic synthesis as an important intermediate. It can be used to synthesize drugs, pesticides and other organic compounds.
Method:
The method of preparation is as follows:
1. By 2-fluoropyridine and a certain amount of methyl bromide in the presence of oxidant chlorine or carbon peroxide reaction.
2. It is prepared by the reaction of 2-bromo-5-fluoropyridine and methyl lithium.
Safety Information:
It may be irritating and corrosive to the human body, so you need to pay attention to safety measures when using it, including wearing protective gloves, glasses and protective clothing. Avoid inhaling its vapors or contact with skin and eyes. If inhaled or exposed to the compound, wash the affected area immediately and seek medical help if necessary.
