2-fluoro-4-methylpyridine（CAS# 461-87-0)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. |
| UN IDs | 1993 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | 3 |
| Packing Group | III |
Introduction
2-fluoro-4-methylpyriridine is an organic compound with the chemical formula C6H6FN. It is a colorless liquid with an aroma similar to pyridine.
2-fluoro-4-methylpyridine is widely used in organic synthesis. It is used as a pharmaceutical intermediate and can be used in the synthesis of some anticancer drugs and pesticides. In addition, it can also be used as an organic photoelectric material and a catalyst intermediate.
There are two main methods for preparing 2-fluoro-4-methylpyridine. One is the reaction of benzoic acid and sulfuric acid to give pyridine-4-one, followed by reaction with hydrofluoric acid to give 2-fluoro-4-methylpyridine. The other is obtained by heating 2-fluoropyridine and acetic anhydride in acetic acid.
When using 2-fluoro-4-methylpyridine, you need to pay attention to its safety. It is a flammable liquid and should be stored in a cool, ventilated place, away from fire sources and oxidants. Contact with skin and eyes may cause irritation and burns, so wear protective gloves and goggles during operation. If accidentally inhaled or ingested, should seek medical attention.
