2-(chloromethyl)-5-(trifluoromethyl)-1 3 4-oxadiazole（CAS# 723286-98-4)

Introduction

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole is an organic compound with the formula C4H2ClF3N2O.

Nature:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole is a colorless to pale yellow liquid or crystalline solid. It has high thermal stability and chemical inertness. It is insoluble in water at room temperature, soluble in some organic solvents such as ethanol and ether. The compound can be characterized by techniques such as nuclear magnetic resonance and mass spectrometry.

Use:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole has certain application value in the field of chemistry. It is often used as an intermediate in organic synthesis for the synthesis of other compounds. In addition, it is also used as a research reagent in the field of pesticides and medicine.

Preparation Method:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole can be synthesized by a variety of methods. The following is a common preparation method:

1. Add a catalyst (such as triethylamine) to an anhydrous organic reaction solvent system.

2. Add a certain amount of methyl 3-chloropropionate and methyl trifluoroformate to the solvent system.

3. The reaction is carried out at a suitable temperature under an inert atmosphere, and it is usually necessary to heat the reaction mixture.

4. Filtration or distillation to obtain the product, after appropriate purification and drying to obtain pure product.

Safety Information:

2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole is generally relatively safe when used and stored correctly. However, as an organic compound, it may cause certain harm to human health and the environment. In use and handling, should follow the correct safety procedures, and avoid direct contact. The relevant safety instructions for the compound should be carefully read and followed. If necessary, the operation should be carried out under the guidance of professional personnel.