2-Chlorobenzonitrile（CAS# 873-32-5)
Risk and Safety
| Hazard Symbols | Xn – Harmful |
| Safety Description | S23 – Do not breathe vapour. |
| UN IDs | UN 3439 |
Introduction
Nature:
1. It is a white crystalline solid that is non-volatile at room temperature.
2. It has a spicy cyanide flavor and is easily soluble in ethanol, chloroform, and acetonitrile.
Usage:
1. It is an important organic synthesis intermediate with extensive applications in the fields of dyes and other organic chemicals.
2. It can be used to synthesize compounds such as herbicides, dyes, and rubber preservatives.
Method:
The synthesis method of 2-chlorobenzonitrile is usually obtained by reacting chlorobenzene with sodium cyanide. Firstly, under alkaline conditions, chlorobenzene reacts with sodium cyanide to form chlorophenylcyanide, which is then hydrolyzed to obtain 2-chlorobenzonitrile.
Security:
1. Has certain toxicity. Contact or inhalation may cause eye and skin irritation, and even damage.
2. Wear appropriate personal protective equipment during operation to avoid contact with skin and respiratory tract.
3. During the handling process, safety operating procedures should be followed to avoid accidents.
