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2-Chloro-5-pyridineacetonitrile(CAS# 39891-09-3)

Chemical Property:

Molecular Formula C7H5ClN2
Molar Mass 152.58
Density 1.262±0.06 g/cm3(Predicted)
Melting Point 49-54°C
Boling Point 182 °C(Press: 1 Torr)
Flash Point >110℃
Vapor Presure 0.00166mmHg at 25°C
pKa -1.02±0.10(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index 1.553

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Risk and Safety

Risk Codes R22 – Harmful if swallowed
R37/38 – Irritating to respiratory system and skin.
R41 – Risk of serious damage to eyes
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 – Wear eye / face protection.
UN IDs UN 3439 6.1 / PGIII
WGK Germany 3
Hazard Class IRRITANT, TOXIC

2-Chloro-5-pyridineacetonitrile(CAS# 39891-09-3) Introduction
2-Chloro-5-acetonitrile pyridine is an organic compound. It has white crystals or solids and is soluble in organic solvents such as ethanol and chloroform.
It can be used as an intermediate for the synthesis of new drug molecules and bioactive compounds, and is used to synthesize a variety of compounds with antibacterial, antiviral, anticancer and other activities. It can also be used to prepare pesticides, herbicides and weed control agents.

The preparation method of 2-chloro-5-acetonitrile pyridine can be obtained by reacting 2-acetonitrile pyridine with hydrogen chloride. The specific reaction conditions can be optimized and adjusted according to laboratory needs.
It is an organic compound with potential toxicity and irritation. Wear appropriate protective equipment such as laboratory gloves, glasses and laboratory coats during operation. Avoid contact with skin, eyes and other sensitive parts. During storage, it should be stored in a closed container away from open flames and high temperatures. When disposing of waste, it should be handled in accordance with local environmental regulations, and it is prohibited to discharge it into water sources or soil. During use and handling, follow relevant safety operating procedures and strictly control personal exposure.


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