2-Chloro-5-fluorobenzaldehyde(CAS# 84194-30-9)
Risk and Safety
Risk Codes | R22 – Harmful if swallowed R37/38 – Irritating to respiratory system and skin. R41 – Risk of serious damage to eyes |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. |
Hazard Class | IRRITANT |
Introduction
-Appearance: White crystal or light yellow solid.
-Melting point: about 40-42 ℃.
-Boiling point: about 163-165 ℃.
-Density: about 1.435g/cm³.
-Solubility: It is soluble in some common organic solvents, such as ethanol, chloroform and dichloromethane.
Use:
It is mainly used for chemical reactions in organic synthesis. It can be used as an intermediate of fluorescent dyes, as a raw material in the pharmaceutical field, and in the agricultural field for the preparation of pesticides.
Preparation Method:
can be prepared by chlorination, fluorinated benzaldehyde method. The specific preparation method is as follows:
1. Under appropriate conditions, hydrofluoric acid is added to benzaldehyde to allow it to undergo a fluorination reaction.
2. After the reaction, hydrogen chloride is added to chlorinate the fluorinated product.
3. carry out the appropriate purification steps to obtain pure phosphonium.
Safety Information:
-is harmful substances, may cause irritation and damage to the human body. Wear protective gloves, glasses and respiratory protective equipment when necessary.
-Avoid inhaling its dust or gas, and avoid contact with skin and eyes.
-During storage and use, chemical safety procedures should be observed, and proper ventilation conditions should be maintained.
-For accidental exposure or ingestion, seek medical attention immediately and provide appropriate safety data.