2-Chloro-3-fluoro-5-methylpyridine（CAS# 34552-15-3)
| Hazard Symbols | Xi – Irritant |
| Hazard Class | IRRITANT |
Introduction
It is an organic compound with the chemical formula of C6H5ClFN. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: It is a colorless to light yellow liquid.
-Boiling point: approximately 126-127°C.
-Density: about 1.36g/cm³.
-Solubility: Soluble in many organic solvents, such as ethanol, ether and dimethylformamide.
Use:
-is widely used as an intermediate in organic synthesis and can be used to synthesize other organic compounds.
-It can also be used as a starting material for drug synthesis, pesticide synthesis and dye synthesis.
Preparation Method:
-or can be prepared by the halogenation reaction of pyridine. First, pyridine and acetic acid undergo a chlorination reaction to produce 2-chloropyridine. The 2-chloropyridine is then converted to 2-chloro-3-fluoropyridine by a fluorination reaction. Finally, 2-chloro-3-fluoropyridine was methylated using a methylation reaction.
Safety Information:
-is an irritating compound that may irritate the eyes and skin.
-During use and handling, appropriate safety measures should be taken, including wearing protective glasses and gloves.
-Avoid inhaling the vapor of the compound and ensure that it is operated in a well-ventilated environment.
-When storing and handling, keep away from fire and oxidizing agents to avoid the risk of fire and explosion.
-During use, attention should be paid to complying with relevant safety operation procedures and regulations.
