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2-(Bromomethyl)-5-(trifluoromethyl)furan(CAS#17515-77-4)

Chemical Property:

Molecular Formula C6H4BrF3O
Molar Mass 228.99
Density 1.693±0.06 g/cm3(Predicted)
Boling Point 38 °C
Flash Point 230.4°C
Solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
Vapor Presure 1.5E-08mmHg at 25°C
Appearance Oil
Color Clear Colourless
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index 1.45

Product Detail

Product Tags

Hazard Symbols C – Corrosive
Risk Codes R34 – Causes burns
R36/37/38 – Irritating to eyes, respiratory system and skin.
R43 – May cause sensitization by skin contact
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37 – Wear suitable protective clothing and gloves.
UN IDs 1760
Hazard Note Corrosive
Hazard Class 8
Packing Group

 

Introduction

2-(bromomethyl)-5-(trifluoromethyl)furan is an organic compound with the chemical formula C8H9BrO4. Its nature is as follows:

 

1. Appearance: 2-(bromomethyl)-5-(trifluoromethyl)furan is a colorless to light yellow liquid.

2. Solubility: It can be dissolved in water or organic solvents.

3. Melting point and boiling point: It has a relatively high melting point and boiling point, 62-65 ℃ and 210-215 ℃, respectively.

4. Hydrolysis: 2-(bromomethyl)-5-(trifluoromethyl)furan is easy to hydrolyze, which is more obvious under alkaline conditions.

 

The compound has certain applications in the pharmaceutical and chemical industries:

 

1. Medical Use: 2-(bromomethyl)-5-(trifluoromethyl)furan is a stimulant, commonly used in the treatment of central nervous system diseases.

2. Chemical use: It is an important intermediate, which can be used in organic synthesis and preparation of other organic compounds.

 

Method:

 

2-(bromomethyl)-5-(trifluoromethyl)furan can be synthesized by the following steps:

 

1. The monomethylfuran is reacted with Methylene bromide to produce 2-(bromomethyl) furan.

2.2.2-(bromomethyl) furan reacts with methanol to produce 2-(bromomethyl)-5-(trifluoromethyl)furan through acid catalysis.

 

Safety Information:

 

1. 2-(bromomethyl)-5-(trifluoromethyl)furan is an organic compound. Exposure or inhalation may cause health hazards. Therefore, safe operating procedures should be followed when using it.

2. It is irritating to the eyes and skin. After contact, rinse with plenty of water immediately and seek medical help.

3. During storage and handling, avoid contact with oxidants and strong acids to prevent harmful reactions.

4. Before use, read the safety technical manual of the product, and properly keep the compound, avoid contact with combustibles and store in a high temperature environment.


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