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2-Bromoacetophenone(CAS#70-11-1)

Chemical Property:

Molecular Formula C8H7BrO
Molar Mass 199.04
Density 1.476
Melting Point 48-51 °C (lit.)
Boling Point 135 °C/18 mmHg (lit.)
Flash Point >230°F
Water Solubility PRACTICALLY INSOLUBLE
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Vapor Presure 0.0184mmHg at 25°C
Appearance Crystals or Powder
Color White to dark green-brown
Merck 14,1402
BRN 606474
Storage Condition 2-8°C
Stability Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
Refractive Index 1.5700 (estimate)
Physical and Chemical Properties Melting Point: 48 – 51 ℃Boiling Point: 135 at 18mm Hg
Use Used as a pharmaceutical Intermediate

Product Detail

Product Tags

Hazard Symbols C – Corrosive
Risk Codes R34 – Causes burns
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN 2645 6.1/PG 2
WGK Germany 3
FLUKA BRAND F CODES 8-19
TSCA Yes
HS Code 29143990
Hazard Note Corrosive
Hazard Class 6.1
Packing Group II

 

Introduction

α-bromoacetophenone is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of α-bromoacetophenone:

 

Quality:

1. Appearance: α-bromoacetophenone is a colorless or yellowish liquid.

2. Solubility: soluble in organic solvents, such as ethanol and ether.

 

Use:

1. Organic synthesis intermediates: α-bromoacetophenone is often used as an organic synthesis intermediate, which can be used to synthesize organic compounds with specific molecular structures and functions.

 

Method:

The preparation method of α-bromoacetophenone can be carried out by the following steps:

1. Acetophenone is reacted with hydrogen bromide to produce bromoacetophenone.

2. The reaction is carried out under alkaline conditions, and the bromoacetophenone is α halogenated to generate α-bromoacetophenone.

 

Safety Information:

1. α-Bromoacetophenone is irritating and should be avoided from contact with skin and eyes.

2. Safety measures such as protective gloves, glasses, and a lab coat should be used during use and handling.

3. When storing, it should be sealed, protected from light, ventilated, and away from flammable substances.

4. Waste disposal should comply with local regulations and regulations.


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