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2-Bromo thiazole(CAS#3034-53-5)

Chemical Property:

Molecular Formula C3H2BrNS
Molar Mass 164.02
Density 1.82 g/mL at 25 °C (lit.)
Melting Point 171 C
Boling Point 171 °C (lit.)
Flash Point 146°F
Water Solubility insoluble
Solubility Chloroform, Dichloromethane
Vapor Presure 1.9mmHg at 25°C
Appearance Liquid
Specific Gravity 1.836
Color Clear colorless to orange-brown
BRN 105724
pKa 0.84±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index n20/D 1.593(lit.)
Use As an intermediate in the preparation of 2-acetylthiazole

Product Detail

Product Tags

Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S23 – Do not breathe vapour.
S24/25 – Avoid contact with skin and eyes.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs 1993
WGK Germany 3
TSCA Yes
HS Code 29341000
Hazard Class IRRITANT, FLAMMABLE

 

Introduction

2-Bromothiazole is an organic compound.

 

Its properties are as follows:

Appearance: 2-Bromothiazole is a white crystalline solid;

Solubility: It is insoluble in water, but soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide;

Stability: It is relatively stable to air and light.

 

2-Bromothiazole is commonly used as a reaction intermediate and reagent in organic synthesis, and the specific uses are as follows:

Biochemical research: 2-Bromothiazole can also be used as a probe or labeling reagent in biochemistry laboratories for testing, researching, and analyzing biomolecules or metabolic processes.

 

There are many ways to prepare 2-bromothiazole, and one of the commonly used methods is to use bromide to react directly with thiazole. The specific preparation method is as follows:

thiazole is dissolved in ethylene oxide, and then bromine is added to allow it to react; After the end of the reaction, the product is crystallized and purified, that is, 2-bromothiazole is obtained.

 

When using and handling 2-bromothiazole, the following safety information should be noted:

Avoid skin contact: 2-bromothiazole is irritating and may cause inflammation or allergic reactions in contact with the skin, so direct contact should be avoided;

Ventilation: 2-bromothiazole has a certain volatility, and a well-ventilated environment should be maintained when used to avoid inhaling high concentration of gas;

Fire and explosion prevention: 2-bromothiazole is a combustible substance, which should be kept away from open flames and high temperatures to avoid fire or explosion accidents;

Storage Caution: 2-Bromothiazole should be stored in a cool, dry, ventilated place, away from oxidants and ignition sources.

 

In summary, 2-bromothiazole is an organic compound with a wide range of applications, which is commonly used in organic synthesis and biochemical research. Attention should be paid to relevant safety information when using to ensure the safety of operation.


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