2-Bromo-5-nitropyridine（CAS# 4487-59-6)
| Risk Codes | R25 – Toxic if swallowed R41 – Risk of serious damage to eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
Introduction
2-Bromo-5-nitropyridine is an organic compound with the chemical formula C5H3BrN2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Bromo-5-nitropyridine is a white solid with a slight oxalic acid taste. It has high thermal and chemical stability. Slightly soluble in water at room temperature, soluble in organic solvents such as ethanol and acetone.
Use:
2-Bromo-5-nitropyridine has a wide range of applications. It is an important raw material and intermediate in organic synthesis. It can be used in the synthesis of pesticides, dyes, photosensitive materials and pharmaceutical compounds. In addition, it can also be used as a catalyst and a ligand.
Preparation Method:
2-Bromo-5-nitropyridine synthesis methods are mainly the following:
1. by 2-bromopyridine and nitric acid reaction under acidic conditions.
2. by 3-bromopyridine and sodium nitrite reaction under alkaline conditions.
Safety Information:
2-Bromo-5-nitropyridine is a toxic compound with certain dangers. Pay attention to the following safety precautions during use and storage:
1. avoid inhalation of dust or vapor, should be in a well-ventilated place to operate.
2. avoid contact with skin, eyes and mucous membranes, such as contact should immediately rinse with plenty of water, and seek medical help.
3. pay attention to fire and explosion prevention measures, avoid contact with flammable materials.
4. Store in a sealed container, away from fire and oxidant.
5. Dispose of according to local regulations to avoid direct discharge to the environment.
Summary:
2-Bromo-5-nitropyridine is an organic compound with a wide range of applications. However, due to its toxicity, it is necessary to pay attention to safe operation, proper storage and disposal of residual materials.
