2-Bromo-5-chloropyridine（CAS# 40473-01-6)
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R20/22 – Harmful by inhalation and if swallowed. R20/2236/37/38 - R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 – Do not breathe dust. S22 26 36/37/39 - S36 – Wear suitable protective clothing. |
| UN IDs | Cool, dry,tightly closed |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
Introduction
2-Bromo-5-chloropyridine is an organic compound, the following is an introduction to some properties, uses, preparation methods and safety information of 2-bromo-5-chloropyridine:
Quality:
1. Appearance: 2-bromo-5-chloropyridine is a colorless to pale yellow solid.
3. Solubility: 2-bromo-5-chloropyridine has good solubility in common organic solvents, such as ethanol, acetone and dimethyl thionite ether.
Use:
1. Chemical reagents: 2-bromo-5-chloropyridine is often used as a reagent in organic synthesis.
2. Pesticide intermediates: It is also used in the synthesis of intermediates of pesticides as raw materials for insecticides or herbicides.
Method:
The preparation of 2-bromo-5-chloropyridine can be obtained by the reaction of 2-chloropyridine with hydrobromic acid. The specific steps include dissolving 2-chloropyridine in anhydrous cyclohexane, adding hydrobromic acid, heating the reaction and stirring, after the reaction is completed, the resulting organic phase is separated with water and saturated sodium chloride solution, and the target product is purified by drying treatment and distillation.
Safety Information:
1. 2-Bromo-5-chloropyridine has potential carcinogenic effects and toxicity to the reproductive system, and precautions should be taken during use.
2. Avoid contact with skin and eyes.
3. When using and storing, it should be kept away from fire and heat sources.
4. Good ventilation conditions should be maintained during operation.
5. Please strictly follow the relevant safety procedures and use personal protective equipment.
