2-BROMO-3-METHOXYPYRIDINE（CAS# 24100-18-3)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R22 – Harmful if swallowed R37/38 – Irritating to respiratory system and skin. R41 – Risk of serious damage to eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. |
| WGK Germany | 3 |
| HS Code | 29333990 |
Introduction
2-bromo-3-methoxypyridine is an organic compound with the chemical formula C6H6BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in anhydrous ethanol and Ether solvents
-Boiling point: 167-169 ° C
-Density: 1.568 g/mL
Use:
2-bromo-3-methoxypyridine has certain applications in the field of chemistry:
-As an intermediate: can be used to synthesize other organic compounds, such as drugs, pesticides and dyes.
-Organic synthesis: It can participate in a variety of different reactions, such as electrophilic substitution reactions, condensation reactions, etc.
Method:
2-bromo-3-methoxypyridine synthesis methods are mainly the following:
1. By the reaction of 3-methoxypyridine and bromine: 3-methoxypyridine is reacted with bromine and heated under alkaline conditions to obtain the product 2-bromo-3-methoxypyridine.
2. By the reaction of pyridine and 2-Bromo methyl ether: pyridine and 2-Bromo methyl ether reaction, under appropriate conditions for heating or using a catalyst to generate the desired product.
Safety Information:
The security of 2-bromo-3-methoxypyridine needs attention. The following are some security tips:
-Avoid inhalation, contact with skin, or entering eyes. Wear appropriate protective equipment such as gloves, goggles and face shields during use.
-When storing, it should be placed in a well-ventilated place, away from fire and oxidizing agents.
-Read the relevant safety data sheet carefully before use and use it in accordance with the correct operating procedures.
