2 6-Dibromo-4-(trifluoromethyl)aniline（CAS# 72678-19-4)
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29214300 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
Introduction
4-Amino-3,5-dibromobenzotrifluoride is an organic compound with the chemical formula C7H4Br2F3N. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless or light yellow solid
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
-melting point: about 115-117 ℃
-Boiling point: about 285 ℃
Use:
4-Amino-3,5-dibromobenzotrifluoride has certain application value and is often used in the following aspects:
-As an intermediate in organic synthesis, it can be used to prepare other compounds, such as drugs, pesticides and dyes.
-In chemical research, it can be used as a reagent for deprotection reaction.
Preparation Method:
4-Amino-3,5-dibromobenzotrifluoride can generally be prepared by the following steps:
1.3,5-dibromobenzoic acid was used as raw material to prepare 3,5-dibromobenzoic acid ester by acidification reaction.
2.3,5-dibromobenzoic acid ester is reacted with nitrogen compound to decarboxylate to generate 3,5-dibromobenzene acetyl chloride.
3. react 3,5-dibromobenzotrifluoromethane with 3,5-dibromobenzotrifluoride to generate 4-Amino-3,5-dibromobenzotrifluoride.
4. The pure product can be obtained by crystallization or other purification methods.
Safety Information:
- 4-Amino-3,5-dibromobenzotrifluoride needs to take corresponding safety measures during operation and storage to avoid contact with skin and eyes.
-and to prevent inhalation or ingestion.
-Wear appropriate protective equipment such as chemical gloves, goggles and protective clothing during use.
-In the event of a possible accident or inadvertent contact, rinse immediately with water and seek medical attention.
-When handling the compound, please follow the safety procedures.
