2 5-difluorobenzonitrile(CAS# 64248-64-2)
Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S36/37 – Wear suitable protective clothing and gloves. |
UN IDs | UN 1325 4.1/PG 2 |
WGK Germany | 3 |
HS Code | 29269090 |
Hazard Note | Toxic |
Hazard Class | 6.1 |
Packing Group | III |
Introduction
2,5-Difluorobenzonitrile is an organic compound. The following is an introduction to some properties, uses, preparation methods and safety information of 2,5-difluorobenzonitrile:
Quality:
- 2,5-Difluorobenzonitrile is a colorless to pale yellow crystal with a pungent odor.
- 2,5-difluorobenzonitrile is almost insoluble in water at room temperature, but soluble in organic solvents such as ethanol, acetone, etc.
- It is a compound with a strong aromatic odor.
Use:
- 2,5-Difluorobenzonitrile is widely used in organic synthesis as a chemical reagent for the preparation of other organic compounds.
- It is commonly used in fluorination reactions and aromatization reactions because the introduction of fluorine atoms can change the properties of compounds, increasing their hydrophobicity and chemical stability.
Method:
- 2,5-difluorobenzonitrile can be prepared by aromatic substitution reaction. A common preparation method is to react para-dinitrobenzene with nitrosamines catalyzed by cuprous chloride and hydrofluoric acid to obtain 2,5-difluorobenzonitrile.
Safety Information:
- When handling 2,5-difluorobenzonitrile, wear appropriate protective equipment such as chemical protective gloves, goggles, and a lab coat.
- It is an irritating compound that may cause irritation to the eyes, skin, and respiratory tract.
- Inhalation of its vapours or dust, skin and eye contact should be avoided during handling.
- Attention should be paid to fire and explosion prevention measures during storage and use, and keep away from fire sources and oxidants.