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2 5-difluorobenzonitrile(CAS# 64248-64-2)

Chemical Property:

Molecular Formula C7H3F2N
Molar Mass 139.1
Density 1.2490 (estimate)
Melting Point 33-35 °C (lit.)
Boling Point 188 °C
Flash Point 172°F
Vapor Presure 0.0946mmHg at 25°C
Appearance White solid
Color White or Colorles to Yellow to Orange
BRN 2085640
Storage Condition Sealed in dry,Room Temperature
Refractive Index 1.496
MDL MFCD00001777
Physical and Chemical Properties White solid. Boiling point 188 °c, melting point 33 °c -35 °c, flash point 77 °c.

Product Detail

Product Tags

Risk Codes R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S36/37 – Wear suitable protective clothing and gloves.
UN IDs UN 1325 4.1/PG 2
WGK Germany 3
HS Code 29269090
Hazard Note Toxic
Hazard Class 6.1
Packing Group III

 

Introduction

2,5-Difluorobenzonitrile is an organic compound. The following is an introduction to some properties, uses, preparation methods and safety information of 2,5-difluorobenzonitrile:

 

Quality:

- 2,5-Difluorobenzonitrile is a colorless to pale yellow crystal with a pungent odor.

- 2,5-difluorobenzonitrile is almost insoluble in water at room temperature, but soluble in organic solvents such as ethanol, acetone, etc.

- It is a compound with a strong aromatic odor.

 

Use:

- 2,5-Difluorobenzonitrile is widely used in organic synthesis as a chemical reagent for the preparation of other organic compounds.

- It is commonly used in fluorination reactions and aromatization reactions because the introduction of fluorine atoms can change the properties of compounds, increasing their hydrophobicity and chemical stability.

 

Method:

- 2,5-difluorobenzonitrile can be prepared by aromatic substitution reaction. A common preparation method is to react para-dinitrobenzene with nitrosamines catalyzed by cuprous chloride and hydrofluoric acid to obtain 2,5-difluorobenzonitrile.

 

Safety Information:

- When handling 2,5-difluorobenzonitrile, wear appropriate protective equipment such as chemical protective gloves, goggles, and a lab coat.

- It is an irritating compound that may cause irritation to the eyes, skin, and respiratory tract.

- Inhalation of its vapours or dust, skin and eye contact should be avoided during handling.

- Attention should be paid to fire and explosion prevention measures during storage and use, and keep away from fire sources and oxidants.


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