2 4-Pyrrolidinedione（CAS# 37772-89-7)

Introduction

2,4-Pyrrolidinedione, also known as 2,4-pyrrolidinedione, has a CAS number of 37772-89-7.

Quality:

- Appearance: 2,4-pyrrolidinedione is a colorless to white crystalline powder.

- Solubility: It is less soluble in water but soluble in many organic solvents such as alcohols, ethers, and ketones.

Use:

2,4-pyrrolidinedione is widely used in chemical synthesis and has the following main uses:

- As a peptide synthesis and amino acid protecting group.

Method:

There are many preparation methods for 2,4-pyrrolidoneione, and the common methods are as follows:

- Robinson method: 2,4-pyrrolidinedione is obtained by the reaction of 2,4-succinic acid and ammonia.

- Acetonitrile oxidation method: 2,4-pyrrolidinedione is generated by the reaction of acetonitrile with oxygen in the presence of an aluminum catalyst.

Safety Information:

2,4-pyrrolidinedione is a commonly used intermediate in chemical synthesis and generally has low toxicity. As a chemical substance, the following safety measures should still be noted:

- 2,4-pyrrolidinedione should be kept away from ignition and oxidants.

- Appropriate personal protective equipment such as lab gloves and goggles should be worn during operation.

- When storing, it should be kept tightly sealed in a dry, cool place and avoid mixing with other chemicals.