2 4 5-Trifluorobenzoic acid（CAS# 446-17-3)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29163990 |
| Hazard Class | IRRITANT |
Introduction
2,4,5-Trifluorobenzoic acid is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
- Appearance: Colorless to white crystalline powder
- Solubility: slightly soluble in water and soluble in organic solvents such as alcohols, ethers and ketones
- Chemical properties: It is a strong acid that reacts with alkalis, metals and reactive metals.
Use:
- 2,4,5-Trifluorobenzoic acid is mainly used as an important intermediate and catalyst in organic synthesis.
- In some specific reactions, it can be used as a source of fluoride ions and participate in fluorination reactions.
- It can also be used in the preparation of other organofluorine compounds.
Method:
There are various ways to prepare 2,4,5-trifluorobenzoic acid, and the following is one of the commonly used methods:
- React benzoic acid with aluminum trifluoride to obtain benzoylaluminum trifluoride.
- Then, benzoyl aluminum trifluoride is reacted with water or alcohol to hydrolyze to give 2,4,5-trifluorobenzoic acid.
Safety Information:
- 2,4,5-Trifluorobenzoic acid is irritating to the skin and eyes, and appropriate protective equipment is required when handling and contacting.
- In a humid environment, it may degrade and produce harmful gases, which need to be operated in a well-ventilated area.
- When storing and transporting, contact with strong oxidants, strong acids and other substances should be prevented.
- Seek medical attention immediately if ingested or inhaled.
Proper operating procedures and safety measures must be followed when using and handling chemicals, and assessed and managed on a case-by-case basis.
