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2 2 2-Trifluoroethylamine hydrochloride(CAS# 373-88-6)

Chemical Property:

Molecular Formula C2H5ClF3N
Molar Mass 135.52
Density 1,24g/cm
Melting Point 220-222°C (subl.)(lit.)
Boling Point 36°C at 760 mmHg
Water Solubility It is Soluble in 0.7 to water, but soluble in ethanol and chloroform, slightly soluble in benzene, hardly soluble in ether.
Vapor Presure 501mmHg at 25°C
Appearance White to yellow crystals
Color White to Light yellow to Light orange
BRN 3652103
Storage Condition Inert atmosphere,Room Temperature
Sensitive Hygroscopic
Refractive Index 1,3-1,302
MDL MFCD00012875
Use 2,2,2-Trifluoroethylamine hydrochloride was used in the derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative.

Product Detail

Product Tags

Risk Codes R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S36/37 – Wear suitable protective clothing and gloves.
S24/25 – Avoid contact with skin and eyes.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS KS0250000
FLUKA BRAND F CODES 3-10-21
TSCA T
HS Code 29211990
Hazard Note Hygroscopic/Toxic
Hazard Class IRRITANT
Packing Group III
Toxicity LD50 unr-mus: 476 mg/kg 11FYAN 3,81,63

 

Introduction

2,2,2-Trifluoroethylamine hydrochloride, also known as TFEA hydrochloride. It is a colorless crystalline solid. The following is a detailed introduction to the properties, uses, preparation methods and safety information of TFEA hydrochloride:

 

Quality:

1. Appearance: colorless crystalline solid.

3. Solubility: soluble in water and common organic solvents, such as alcohols, ethers, ketones, etc.

4. Stability: Good stability, not easy to decompose.

 

Use:

1. As a catalyst in organic synthesis: TFEA hydrochloride is often used as a catalyst in organic synthesis reactions, such as esterification, alkylation and other reactions.

2. As a solvent: With its good solubility, TFEA hydrochloride can be used as an organic solvent, e.g. in chemical synthesis to dissolve reactants or catalysts.

3. Other applications: TFEA hydrochloride can also be used in proton conduction membranes, microelectronic devices and other fields.

 

Method:

The preparation method of TFEA hydrochloride is generally to react 2,2,2-trifluoroethylamine with hydrochloric acid to generate TFEA hydrochloride.

 

Safety Information:

1. TFEEA hydrochloride is relatively stable under normal conditions, but may decompose under high temperature and humidity conditions.

2. When using, avoid contact with strong oxidants, strong acids and other substances to prevent dangerous reactions.

3. In case of accidental contact with eyes, skin or inhalation, rinse immediately with plenty of water and seek medical advice.

4. During operation or storage, good ventilation measures should be taken to avoid inhaling dust.

5. When using TFEA hydrochloride, pay attention to follow the relevant safety operation procedures and wear appropriate protective equipment.


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