2 2 2-Trifluoroethylamine （CAS# 753-90-2)
| Risk Codes | R11 – Highly Flammable R34 – Causes burns R52/53 – Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R22 – Harmful if swallowed |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S25 – Avoid contact with eyes. S16 – Keep away from sources of ignition. S61 – Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 2733 3/PG 2 |
| WGK Germany | 3 |
| RTECS | KS0175000 |
| FLUKA BRAND F CODES | 3-10-13 |
| TSCA | T |
| HS Code | 29211990 |
| Hazard Note | Corrosive/Toxic/Flammable |
| Hazard Class | 3 |
| Packing Group | II |
| Toxicity | LC50 ihl-mus: 4170 mg/m3/2H 85JCAE -,606,86 |
Introduction
2,2,2-Trifluoroethylamine is an organic compound with the chemical formula C2H4F3N. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
1. Appearance: 2,2,2-Trifluoroethylamine is a colorless transparent liquid.
2. Odor: It has a pungent odor.
3. Density: 1.262g/mLat 20°C(lit.).
4. Boiling Point: 36-37°C(lit.)
5. Melting Point: -78°C.
6. Solubility: Almost insoluble in water, soluble in organic solvents such as alcohols, ethers and ketones.
Use:
1. Application in organic synthesis: 2,2,2-trifluoroethylamine can be used as an amination reagent in organic synthesis for the introduction of amino groups.
3. Electronics industry: 2,2,2-trifluoroethylamine can be used as a cleaning agent, solvent and refrigerant in the electronics industry.
Method:
There are two common preparation methods for 2,2,2-trifluoroethylamine:
1. By gas fluorination reaction: ethylamine is exposed to fluorine gas, and fluorination is carried out under alkali catalysis to obtain 2,2,2-trifluoroethylamine.
2. Aminoation reaction: 2,2,2-trifluoroethylamine is prepared by reacting ammonia with 1,1,1-trifluoroethane in the presence of a catalyst.
Safety Information:
1. 2,2,2-Trifluoroethylamine is irritating to the skin, eyes and respiratory tract, and should be rinsed with plenty of water immediately after contact.
2. Long-term exposure can be harmful to health and prolonged exposure should be avoided.
3. It should be used in a well-ventilated place and away from fire.
4. It should be stored properly to avoid contact with oxidants and strong alkalis.
5. Wear protective glasses, gloves and a breathable protective mask.
