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(1S 2S)-(-)-1 2-Diphenyl-1 2-ethanediamine(CAS# 29841-69-8)

Chemical Property:

Molecular Formula C14H16N2
Molar Mass 212.29
Density 1.106±0.06 g/cm3(Predicted)
Melting Point 83 °C(Solv: ligroine (8032-32-4))
Boling Point 115 °C(Press: 5 Torr)
Flash Point 199.9°C
Water Solubility Insoluble in water.
Vapor Presure 3.48E-05mmHg at 25°C
Appearance Colorless crystal
pKa 9.78±0.10(Predicted)
Storage Condition Room Temprature
Sensitive Sensitive to air
Refractive Index 1.619
MDL MFCD00082751
Physical and Chemical Properties Melting point 83-85°C(lit.)specific optical rotation -104 o (c = 1.1, MeOH 25 oC)
refractive index -103 ° (C = 1, EtOH)
Storage Conditions 2-8°C

Sensitive Air
BRN 3201645

colorless needle-like crystals, odorless, insoluble in water, soluble in methanol, ethanol, easy oxidation in the air.

Use Applications are widely used in asymmetric synthesis and optical resolution, such as asymmetric hydroxylation reaction of olefins, asymmetric aldol condensation reaction, asymmetric Diels-Alder reaction, asymmetric allylation reaction of carbonyl, synthesis of optically active Allylene alcohols and propynyl alcohols, asymmetric epoxidation of olefins without functional groups, resolution of binaphthol, etc.

Product Detail

Product Tags

Hazard Symbols C – Corrosive
Risk Codes R34 – Causes burns
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN3259

 

Introduction

(1S,2S)-1,2-diphenylethylenediamine, also known as (1S,2S)-1,2-diphenyl-1,2-ethanediamine, is an organic amine compound. The following is an introduction to its properties, uses, preparation methods and safety:

 

Quality:

 

Appearance: White crystalline powder

Solubility: soluble in alcohols, ethers and ketones, insoluble in water

Molecular Formula: C14H16N2

Molecular weight: 212.29 g/mol

 

Uses: (1S,2S)-1,2-diphenylethylenediamine has a wide range of applications in the chemical and pharmaceutical industries:

 

Chiral ligand: It acts as a chiral ligand and can be used to catalyze asymmetric synthesis, especially for the synthesis of chiral organic molecules.

Dye synthesis: It can be used as an intermediate in the synthesis of organic dyes.

Copper-nickel alloy coating: It can also be used as an additive in the preparation of copper-nickel alloy coatings.

 

Method: (1S,2S)-1,2-diphenylethylenediamine can be synthesized by the following steps:

 

Sulfoxide chloride and phenylformaldehyde are added to ethylene glycol dimethyl ether to form diphenyl methanol.

Diphenylmethanol is reacted with triethylamine in acetonitrile to generate (1S,2S)-1,2-diphenylethylenediamine.

 

Safety: The use of (1S,2S)-1,2-diphenylethylenediamine is relatively safe when properly handled and stored. However, as any chemical, it still needs to follow proper laboratory safety operating procedures. Avoid contact with skin and eyes, and avoid inhalation or swallowing. Protective gloves and goggles should be worn when in use, and operated in a well-ventilated environment. In case of accidental exposure or inhalation, seek medical attention and provide information about the chemical.


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