(1R,2R)-1,2-Bis(methanesulfonyloxymethyl)cyclohexane(CAS#186204-35-3)

Introduction

(1R,2R)-1,2-bis (methanesulfonyloxymethyl)cyclohexane, also known as MTS-CH2OH or MTS-OCH2Me, is an organic compound. Its specific properties and uses are as follows:

Nature:

-Appearance: colorless liquid

-Molecular formula: C8H16O4S2

-Molecular weight: 248.35g/mol

-Melting point:-55 ℃

-Boiling point: 170 ℃

-Density: 1.201 g/mL

-Solubility: Soluble in organic solvents, slightly soluble in water

Use:

(1R,2R)-1,2-bis (methanesulfonyloxymethyl)cyclohexane is mainly used as an intermediate in organic synthesis. It is a commonly used protecting group that can be used to protect functional groups such as alcohols, phenols, and amines to prevent unwanted reactions during chemical transformations. Once it is desired to introduce an alcohol, phenol or amine functional group, the protecting group can be removed by reduction or acid catalyzed reaction.

Method:

(1R,2R)-1,2-bis (methanesulfonyloxymethyl)cyclohexane can be synthesized by the following steps:

1. First, cyclohexane is reacted with methanesulfonyl chloride to generate 1,2-bis (methylsulfonylmethyl) cyclohexane.

2. Next, under alkaline conditions, 1,2-bis (methylsulfonylmethyl) cyclohexane and hydrogen peroxide are reacted to give (1R,2R)-1,2-bis (methanesulfonyloxymethyl)cyclohexane.

Safety Information:

(1R,2R)-1,2-bis (methanosulfonyloxymethyl) cyclohexane is generally considered to be relatively safe under regular operations. However, it is still an organic compound, and the following safety measures need to be paid attention:

-Avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water.

-Avoid inhaling its vapor or high concentration of dust, to ensure that the operation in a well-ventilated environment.

-Store it in a closed container when storing, away from fire and oxidizing agents.

-Wear appropriate personal protective equipment during use, such as protective gloves on the laboratory, glasses and protective clothing outside the laboratory.

Please note that the above information is for reference only, the specific use and operation should be carefully read the product manual and follow the relevant safety procedures.