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1H-pyrrolo[2,3-b]pyridine-4-carbonitrile(CAS#344327-11-3)
| Risk Codes | R22 – Harmful if swallowed R37/38 – Irritating to respiratory system and skin. R41 – Risk of serious damage to eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
Introduction
1H-Pyrrolo [2,3-b]pyridine-4-carbonitrile, chemical formula C9H6N4, is an organic compound containing nitrogen and carbon heterocycles. Its properties are as follows:
1. Appearance: 1H-Pyrrolo [2,3-b]pyridine-4-carbonitrile is a white or light yellow crystal powder.
2. Solubility: It is slightly soluble in water at room temperature and can be dissolved in organic solvents such as ethanol, dimethyl sulfoxide and ketones.
3. Stability: The compound is relatively stable under conventional storage conditions.
4. Application: 1H-pyrrolo[2,3-b]pyridine-4-carbonitrile is widely used in organic synthesis, drug research and pesticide research. It can be used as an intermediate in various organic synthesis reactions, as well as in the preparation of indole ketones and other heterocyclic compounds. In addition, it can also be used as an active ingredient of drugs or a key intermediate of pesticides.
5. Preparation method: 1H-yrrolo [2,3-b]pyridine-4-carbonitrile has many preparation methods, and is generally obtained by multi-step synthesis. One of the common preparation methods is the introduction of cyano and nitrogen heterocycles in a series of reaction steps starting from indole.
6. Safety Information: At present, specific information on the toxicity and safety of 1H-Pyrrolo [2,3-b]pyridine-4-carbonitrile is limited. When using or handling, it is recommended to follow the usual laboratory safety practices and take appropriate personal protective measures, such as wearing gloves, goggles and laboratory coats. If necessary, refer to the relevant safety literature and data and follow the relevant laws and regulations.
