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1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid(CAS#952182-02-4)

Chemical Property:

Molecular Formula C7H5N3O2
Molar Mass 163.13
Density 1.617±0.06 g/cm3(Predicted)
Boling Point 475.1±25.0 °C(Predicted)
Flash Point 241.1°C
Vapor Presure 7.85E-10mmHg at 25°C
pKa 10.24±0.40(Predicted)
Storage Condition Sealed in dry,Room Temperature
Refractive Index 1.763

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36 – Irritating to the eyes
Safety Description 26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

 

Introduction

1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid is an organic compound with the chemical formula C9H6N2O2. The following is a description of the properties, uses, preparation and safety information of the compound:

 

Nature:

1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid is a solid. It has a white or off-white crystalline powder shape. The compound has low solubility in water and is soluble in organic solvents such as ethanol and dimethyl sulfoxide. Its melting point is about 270-273 degrees Celsius.

 

Use:

1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid has certain application value in the field of medicine. It is an important drug intermediate, which is widely used in the synthesis of antibiotics, antibacterial drugs and antiviral drugs.

 

Preparation Method:

A commonly used method for preparing 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid is to react with sodium pyrazole as a raw material in the presence of methyl iodide. The specific reaction conditions can be adjusted and optimized according to actual needs.

 

Safety Information:

The safety of 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid has not been specifically evaluated. During handling and use, follow laboratory safety practices and wear appropriate protective equipment. Avoid contact with skin, eyes and respiratory tract. If you come into contact with this substance, rinse immediately with plenty of water and seek medical advice.


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