11-(tert-Butoxycarbonylamino)undecanoic acid(CAS#10436-25-6)
Hazard Symbols | Xi – Irritant |
Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. |
WGK Germany | 3 |
Hazard Class | IRRITANT |
Introduction
Tert-butoxycarbonyl-11-aminoundecanoic acid (BOC-11-aminoundecanoic acid) is an organic compound. It is a white solid that is soluble in organic solvents such as ether or chloroform. BOC-11-aminoundecanoic acid has a variety of uses and is mainly used as a protecting group in organic synthesis. The tert-butoxycarbonyl group (BOC) is a commonly used protective group that protects the amino group from accidental reactions or side reactions during synthesis. The preparation method of BOC-11-aminoundecanoic acid is generally obtained by esterification reaction with aminoundecanoic acid. Tert-butyl tert-butyl ether carbonyl copper chloride (BOC-Cl) was added to the solution of aminoundecanoic acid, and the reaction was carried out under carbonate buffer conditions to obtain BOC-11-aminoundecanoate. Then, BOC-11-aminoundecanoic acid is obtained by alkaline hydrolysis. The safety information of BOC-11-aminoundecanoic acid has not been clearly reported. In general, appropriate personal protective equipment, such as lab gloves and protective glasses, should be worn when handling chemicals to prevent direct contact or inhalation. It should be kept in a cool, dry, well-ventilated place and away from fire and combustible substances. When using BOC-11-aminoundecanoic acid, proper handling methods and laboratory safety guidelines must be followed.