10-Propargyl-10-deazaaminopterin(CAS#146464-95-1)
10-Propargyl-10-deazaaminopterin(CAS#146464-95-1)
introduce
Pralatrexate is an antifolate agent that is structurally similar to folic acid and acts on some cell lines with IC50s below 300 nM.
Brief introduction
10-Parinpropyl-10-desazaminopterin is an organic compound, often abbreviated as EZA. The following is an introduction to the nature, use, manufacturing method and safety information of EZA:
Quality:
- EZA is a white crystalline solid.
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- EZA has high thermal stability and can be stored and used at high temperatures.
Use:
Method:
- The preparation of EZA is usually carried out by chemical synthesis.
- A common preparation method is to react 2,4,5-triaminopyrimidine with n-butynol to obtain EZA.
Safety Information:
- EZA has some toxicity and should be handled with care.
- Appropriate safety measures such as wearing protective gloves, goggles, and protective clothing are required when using and operating EZA.
- EZA should be kept away from ignition sources and oxidants, and avoid contact with flammable materials. During operation, care should be taken to prevent it from inhaling, touching the skin and eyes to avoid adverse reactions.